Twitter can be a noisy bastard. I follow maybe 250 people and there’s no good way to keep up unless that is the only thing I’m doing. Hardly a productive option. Recently I’ve started to use “Tweetdeck”:http://www.tweetdeck.com/ as my twitter client. TweetDeck is a desktop (Adobe Air) app with all sorts of features that help manage my Twitter stream.
My favorite of TweetDeck’s features is its “TwitScoop”:http://www.twitscoop.com/ integration.
One glance at the TwitScoop column running on my second monitor and I can easily spot breaking news or popular topics. Clicking any of the words in the TwitScoop cloud brings me to the TwitScoop search for that word. Very handy.